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Meckel's Diverticulum in Children: A Monocentric Experience and Mini-Review of Literature.

Authors :
Nissen, Matthias
Sander, Volker
Rogge, Phillip
Alrefai, Mohamad
Tröbs, Ralf-Bodo
Source :
Children; Jan2022, Vol. 9 Issue 1, p35-35, 1p
Publication Year :
2022

Abstract

Vitelline duct anomalies (VDA, including Meckel's diverticulum (MD)) result from failed embryologic obliteration. This study aimed for characteristics in symptomatic versus asymptomatic VDA, analyzing clinico-laboratory data from 73 children, aged 1 day to 17 years, treated at a tertiary Pediatric Surgery Institution from 2002–2017. A male preponderance was obtained (ratio 3.6:1). MD accounted for 85% of VDA. Incidence of symptomatic VDA decreased with older age. Leading symptoms were intestinal obstruction and hemorrhage. Mucosal heterotopia (present in 39% of symptomatic MD) was associated with anemia and lowered CRP-levels. On ROC-analysis, hemoglobin < 8.6 g/dL, CRP < 0.6 mg/dL and MD distance to ileocecal valve >40 cm were predictors of ectopic tissue in symptomatic MD. Our data confirmed known characteristics as male preponderance, declined incidence of symptomatic cases with age and predominance of gastric ectopia in symptomatic MD. Moreover, anemia and prolonged distance of MD to ileocecal valve were predictors of ectopic mucosa in symptomatic MD. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
22279067
Volume :
9
Issue :
1
Database :
Complementary Index
Journal :
Children
Publication Type :
Academic Journal
Accession number :
154804887
Full Text :
https://doi.org/10.3390/children9010035