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Immunoglobulin Classification Based on FC* and GC* Features.
- Source :
- Frontiers in Genetics; 1/24/2022, Vol. 13, p1-8, 8p
- Publication Year :
- 2022
-
Abstract
- Immunoglobulins have a pivotal role in disease regulation. Therefore, it is vital to accurately identify immunoglobulins to develop new drugs and research related diseases. Compared with utilizing high-dimension features to identify immunoglobulins, this research aimed to examine a method to classify immunoglobulins and non-immunoglobulins using two features, FC* and GC*. Classification of 228 samples (109 immunoglobulin samples and 119 non-immunoglobulin samples) revealed that the overall accuracy was 80.7% in 10-fold cross-validation using the J48 classifier implemented in Weka software. The FC* feature identified in this study was found in the immunoglobulin subtype domain, which demonstrated that this extracted feature could represent functional and structural properties of immunoglobulins for forecasting. [ABSTRACT FROM AUTHOR]
- Subjects :
- IMMUNOGLOBULIN G
IMMUNOGLOBULINS
CLASSIFICATION
Subjects
Details
- Language :
- English
- ISSN :
- 16648021
- Volume :
- 13
- Database :
- Complementary Index
- Journal :
- Frontiers in Genetics
- Publication Type :
- Academic Journal
- Accession number :
- 154895467
- Full Text :
- https://doi.org/10.3389/fgene.2021.827161