Patient with atopic dermatitis, hyper IgE syndrome and ulcerative colitis, treated successfully with dupilumab during pregnancy.

At 26 years old with a SCORAD of 62 (Figure S1 I ) i with a profound effect on quality of life (DLQI score of 28/30, NRS-itch 9/10 and NRS-sleep 9/10), she began treatment with dupilumab, maintaining the previous treatment with immunoglobulin replacement therapy every 14 days. Treatment efficacy of dupilumab in a hyper-immunoglobulin E syndrome patient with severe atopic dermatitis. [Extracted from the article]