Back to Search Start Over

Chemoproteomic profiling reveals celastrol as a potential modulator of cholesterol signaling.

Authors :
Geng, Yiyun
Xu, Jingyuan
Li, Weichao
Li, Qing
Shen, Chenjinxin
Deng, Zhangshuang
Zhou, Yiqing
Source :
Chemical Communications; 2/11/2022, Vol. 58 Issue 12, p1914-1917, 4p
Publication Year :
2022

Abstract

We report a quantitative chemoproteomic approach that utilizes a clickable photoreactive probe for global profiling of celastrol targets, which may significantly improve the current understanding of celastrol's mode of action. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
CHOLESTEROL

Details

Language :
English
ISSN :
13597345
Volume :
58
Issue :
12
Database :
Complementary Index
Journal :
Chemical Communications
Publication Type :
Academic Journal
Accession number :
155129396
Full Text :
https://doi.org/10.1039/d1cc05986f