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Does Exercise Affect Telomere Length? A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
- Source :
- Medicina (1010660X); Feb2022, Vol. 58 Issue 2, p242, 1p
- Publication Year :
- 2022
-
Abstract
- Background and objectives: Telomere length is an indicator of biological aging, and it shortens during cell division. A short telomere length is associated with various age-related diseases and mortality. It is suggested that physical activity has a positive effect on the rate of telomere length shortening. Materials and Methods: Related studies, published in electronic databases, were searched with keywords, including exercise, telomere length, and randomized controlled trial. The data were weighted and pooled through a fixed-effect model. Results: Of the total 49 studies searched, 7 studies with 939 participants were considered suitable, and were analyzed qualitatively and quantitatively. Exercise is beneficial to telomere length. Aerobic exercise was effective as the type of exercise (MD, −0.03; 95% CI, −0.04 to −0.01). In addition, exercise for more than 6 months, with a change in lifestyle, is beneficial for telomere length (MD, −0.02; 95% CI, −0.04 to −0.01). Conclusions: The type and duration of exercise for positive improvement in telomere length is aerobic exercise for more than 6 months. [ABSTRACT FROM AUTHOR]
- Subjects :
- TELOMERES
AEROBIC exercises
WEIGHT loss
RANDOMIZED controlled trials
Subjects
Details
- Language :
- English
- ISSN :
- 1010660X
- Volume :
- 58
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Medicina (1010660X)
- Publication Type :
- Academic Journal
- Accession number :
- 155499274
- Full Text :
- https://doi.org/10.3390/medicina58020242