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A Case Series of Ketoacidosis After Coronavirus Disease 2019 Vaccination in Patients With Type 1 Diabetes.

A Case Series of Ketoacidosis After Coronavirus Disease 2019 Vaccination in Patients With Type 1 Diabetes.

Authors :
Yakou, Fumiyoshi
Saburi, Masuo
Hirose, Ai
Akaoka, Hiroaki
Hirota, Yusuke
Kobayashi, Takaaki
Awane, Naoko
Asahi, Nobuteru
Amagawa, Toshihiro
Ozawa, Sachihiko
Ohno, Atsushi
Matsushita, Takaya
Source :
Frontiers in Endocrinology; 3/18/2022, Vol. 13, p1-7, 7p
Publication Year :
2022

Abstract

Introduction: We report a case series of severe ketoacidosis after COVID-19 vaccination in a type 1 diabetes patients treated with insulin and an SGLT-2 inhibitor. Case Report: We present two cases of type 1 diabetes mellitus. One patient was treated with insulin therapy and an SGLT-2 inhibitor, and the other patient was treated with insulin therapy alone. Both patients became ill after coronavirus disease-2019 vaccination, making it difficult to continue their diet or insulin injections. On admission, they developed severe diabetic ketoacidosis. This is the first report of ketoacidosis after coronavirus disease-2019 vaccination. Conclusion: The vaccine should be carefully administered to type 1 diabetes patients receiving intensive insulin therapy and a sodium-glucose transporter due to the high risk ketoacidosis. It is important to instruct patients to drink sufficient fluids and to continue insulin injections when they become sick. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
16642392
Volume :
13
Database :
Complementary Index
Journal :
Frontiers in Endocrinology
Publication Type :
Academic Journal
Accession number :
155863930
Full Text :
https://doi.org/10.3389/fendo.2022.840580