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Immunization for Children Living With HIV: A Scoping Review.
- Source :
- Journal of the Pediatric Infectious Diseases Society; Apr2022, Vol. 11 Issue 4, p159-171, 13p
- Publication Year :
- 2022
-
Abstract
- Background Immunosuppression secondary to human immunodeficiency virus (HIV) increases the risk of vaccine-preventable diseases in children living with HIV (CLHIV). Although vaccines are cost-effective interventions, their efficacy, immunogenicity, safety, and persistence of post-vaccination immunity in CLHIV receiving antiretroviral therapy (ART) is unclear. We aimed at identifying existing scientific evidence on immunization of CLHIV generated in the last 10 years to identify the need for a systematic review. Methods Studies were identified using a broad search strategy applied in multiple databases. Included studies involved CLHIV aged 0-10 years and presented outcomes on safety, efficacy, effectiveness, immunogenicity, and use of booster vaccines. Results Nineteen publications were identified. There was variable immunogenicity to and efficacy of vaccines by HIV and ART status. All vaccines were safe. Conclusion The heterogeneity of available studies makes it complex to do a systematic review and meta-analysis. A more uniform approach to sampling and follow-up in future studies would make comparison and interpretation of results more robust. [ABSTRACT FROM AUTHOR]
- Subjects :
- HIV prevention
HIV infections
ONLINE information services
MEDICAL databases
POLIOMYELITIS vaccines
IMMUNIZATION
MEDICAL information storage & retrieval systems
HAEMOPHILUS disease vaccines
DPT vaccines
SYSTEMATIC reviews
AIDS vaccines
ANTIRETROVIRAL agents
PNEUMOCOCCAL vaccines
VACCINE effectiveness
MENINGOCOCCAL vaccines
IMMUNITY
DESCRIPTIVE statistics
ROTAVIRUS vaccines
LITERATURE reviews
MEDLINE
MMR vaccines
CHILDREN
Subjects
Details
- Language :
- English
- ISSN :
- 20487193
- Volume :
- 11
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Journal of the Pediatric Infectious Diseases Society
- Publication Type :
- Academic Journal
- Accession number :
- 156630631
- Full Text :
- https://doi.org/10.1093/jpids/piab119