Vaccine‐induced immune thrombocytopenia and thrombosis: The decline in anti‐platelet factor 4 antibodies is assay‐dependent.

Vaccine-induced immune thrombocytopenia and thrombosis: The decline in anti-platelet factor 4 antibodies is assay-dependent The platelet-activating antibodies in the PIPA have disappeared by 12 weeks post vaccination in most patients,6 although we had at least one patient out of six who had a positive PIPA assay after 14 weeks. Keywords: ELISA; platelet activation; thrombocytopenia; thrombosis; vaccines EN ELISA platelet activation thrombocytopenia thrombosis vaccines 428 430 3 05/10/22 20220515 NES 220515 NICE guidance on the management of vaccine-induced immune thrombocytopenia and thrombosis (VITT) has recently been published.1 This includes recommendations on which laboratory assays should be performed at diagnosis and during recovery, as well as recommendations on anticoagulation and other therapeutic strategies. [Extracted from the article]