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Visible light-driven carbamoyloxylation of the α-C(sp3)–H bond of arylacetones via radical-initiated hydrogen atom transfer.
- Source :
- Chemical Communications; 5/14/2022, Vol. 58 Issue 39, p5845-5848, 4p
- Publication Year :
- 2022
-
Abstract
- Photocatalytic synthesis has emerged as an efficient route to transform CO<subscript>2</subscript> into functionalized organic carbamates by photocatalysis. Herein, a catalyst-free carbamoyloxylation of arylacetones with CO<subscript>2</subscript> and amines under visible light was developed for the synthesis of O-β-oxoalkyl carbamates in yields up to 93%. This protocol proceeded smoothly with the assistance of inexpensive carbon tetrabromide at room temperature under atmospheric CO<subscript>2</subscript> pressure, leading to simultaneous construction of C–O and C–N bonds. Mechanism studies suggested the photoinduced hydrogen atom transfer (HAT) pathway followed by radical addition or single electron transfer (SET). [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 58
- Issue :
- 39
- Database :
- Complementary Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 156914971
- Full Text :
- https://doi.org/10.1039/d2cc01761j