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The case for increasing diversity in tissue-based functional genomics datasets to understand human disease susceptibility.

Authors :
Long, Erping
García-Closas, Montserrat
Chanock, Stephen J.
Camargo, M. Constanza
Banovich, Nicholas E.
Choi, Jiyeon
Source :
Nature Communications; 5/25/2022, Vol. 13 Issue 1, p1-4, 4p
Publication Year :
2022

Abstract

Tissue-based functional genomics resources including molecular quantitative trait loci datasets lack diversity in ancestry and tissue types and thus are inadequate for comprehensively investigating gene regulation. Global efforts to increase the tissue diversity will help achieve more equitable medical care. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Complementary Index
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
157068175
Full Text :
https://doi.org/10.1038/s41467-022-30650-8