Prevalence of hepatitis B virus and associated risk factors among adults patients at Dessie referral and Kemise general hospitals in northeastern Ethiopia.

Background and Aims: Hepatitis is an inflammation of the liver that can reason a variety of health problems and can be fatal. According to the most recent estimates of the Global Burden of Disease study and WHO, viral hepatitis is accountable for around 1.34 million deaths yearly, which is comparable to the yearly number of deaths from HIV/AIDS (1.3 million), malaria (0.9 million), and tuberculosis (1.3 million). This study aimed to assess the prevalence of the Hepatitis B virus and associated risk factors among adults patients at Dessie Referral and Kemise General Hospitals. Methods: The source for the data on Hepatitis B virus (HBV) was all adults aged≥18 years that were admitted and tested for HBV from September 2020 to February 2021 were included in the study. A total of 1283 adults were admitted out of which, 1080 adults have completed measurements and had been taken into consideration for this examination, and others had been excluded from the examination because of exclusion criteria. To meet our objective descriptive statistics, the χ2 test and multiple logistic regression statistical models were used for data analysis. Results: In this study, a total of 1080 adults were included out of which 631 (58.4%) female and 449 (41.6%) were male with a mean age of 34(SD ±± $\pm \,$ 12.56) years. The overall prevalence of HBV among adults was 27.4% (95% confidence interval [CI];24.8–30.2). The results of this study showed that age 25–34(odds ratio [OR] = 3.6, p‐value = 0.005), 35–44 (OR = 6.67, p‐value <0.001), ≥45 (OR = 3.85, p‐value = 0.005), male (OR = 4.36, p‐value < 0.001), history of hospitalization (OR = 0.644, p‐value = 0.04), family history of HBV (OR = 1.96, p‐value = 0.005), and jaundice (OR = 2.50, p‐value = 0.005) were significant risk factors of HBV. Conclusion: The prevalence of HBV in this study is 27.4%. The results of this study showed that age, male, history of hospitalization, family history of HBV, and jaundice were significant risk factors for Hepatitis B virus. [ABSTRACT FROM AUTHOR]