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Recent Advances in Poly(α- L -glutamic acid)-Based Nanomaterials for Drug Delivery.
- Source :
- Biomolecules (2218-273X); May2022, Vol. 12 Issue 5, p636, 26p
- Publication Year :
- 2022
-
Abstract
- Poly(α-L-glutamic acid) (PGA) is a class of synthetic polypeptides composed of the monomeric unit α-L-glutamic acid. Owing to their biocompatibility, biodegradability, and non-immunogenicity, PGA-based nanomaterials have been elaborately designed for drug delivery systems. Relevant studies including the latest research results on PGA-based nanomaterials for drug delivery have been discussed in this work. The following related topics are summarized as: (1) a brief description of the synthetic strategies of PGAs; (2) an elaborated presentation of the evolving applications of PGA in the areas of drug delivery, including the rational design, precise fabrication, and biological evaluation; (3) a profound discussion on the further development of PGA-based nanomaterials in drug delivery. In summary, the unique structures and superior properties enables PGA-based nanomaterials to represent as an enormous potential in biomaterials-related drug delivery areas. [ABSTRACT FROM AUTHOR]
- Subjects :
- NANOSTRUCTURED materials
DRUG delivery systems
Subjects
Details
- Language :
- English
- ISSN :
- 2218273X
- Volume :
- 12
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- Biomolecules (2218-273X)
- Publication Type :
- Academic Journal
- Accession number :
- 157127820
- Full Text :
- https://doi.org/10.3390/biom12050636