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Zinc–proline complex as a novel and efficient catalyst for the green synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones.
- Source :
- Research on Chemical Intermediates; Jun2022, Vol. 48 Issue 6, p2413-2427, 15p
- Publication Year :
- 2022
-
Abstract
- A simple, efficient and green approach to the synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones has been developed via one-pot three-component reaction of aromatic aldehyde, malononitrile and phthalhydrazide catalyzed by zinc–proline complex (Zn[L-proline]<subscript>2</subscript>) using H<subscript>2</subscript>O: PEG<subscript>400</subscript> = 6: 4 as solvent. Atom economy, good to excellent yield, operational simplicity and easy workup are important features of this method. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09226168
- Volume :
- 48
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- Research on Chemical Intermediates
- Publication Type :
- Academic Journal
- Accession number :
- 157133823
- Full Text :
- https://doi.org/10.1007/s11164-022-04728-3