Ocular surface disease is common in moderate‐to‐severe atopic dermatitis patients.

Additionally, occurrence of both AD eyelid involvement and AD facial involvement in the past year was significantly higher in patients with moderate-to-severe OSD compared to patients with no or mild OSD ( I n i = 28 (90.3%) vs. I n i = 18 (46.2%), I p i = <.001 and I n i = 31 (100.0%) vs. I n i = 33 (84.6%), I p i = .030 respectively). Keywords: atopic dermatitis; goblet cell; ocular surface disease EN atopic dermatitis goblet cell ocular surface disease 801 805 5 06/01/22 20220601 NES 220601 Key Messages In a single-centre study, we assessed ocular surface disease prevalence in moderate-to-severe atopic dermatitis. Diagnosing OSD is important since it may be associated with chronic limbitis, possibly leading to irreversible limbal stem cell deficiency and subsequently to irreversible long-term visual loss.3 In our study, lower conjunctival GCD was found in patients with OSD, compared to patients without OSD. However, by comparing GCD of patients with OSD to GCD of healthy controls described in the literature, we can conclude that moderate-to-severe AD patients with OSD have lower GC counts. [Extracted from the article]