Effects of N6-Methyladenosine Modification on Cancer Progression: Molecular Mechanisms and Cancer Therapy.

N⁶-methyladenosine (m⁶A) is a major internal epigenetic modification in eukaryotic mRNA, which is dynamic and reversible. m⁶A is regulated by methylases ("writers") and demethylases ("erasers") and is recognized and processed by m⁶A-binding proteins ("readers"), which further regulate RNA transport, localization, translation, and degradation. It plays a role in promoting or suppressing tumors and has the potential to become a therapeutic target for malignant tumors. In this review, we focus on the mutual regulation of m⁶A and coding and non-coding RNAs and introduce the molecular mechanism of m⁶A methylation involved in regulation and its role in cancer treatment by taking common female malignant tumors as an example. [ABSTRACT FROM AUTHOR]