Back to Search
Start Over
Engineering of hollow polymeric nanosphere-supported imidazolium-based ionic liquids with enhanced antimicrobial activities.
- Source :
- Nano Research; Jun2022, Vol. 15 Issue 6, p5556-5568, 13p
- Publication Year :
- 2022
-
Abstract
- The design of stable, efficient and processable bactericidal materials represents a significant challenge for combating multidrug-resistant bacteria in a variety of engineering fields. Herein, we report a facile strategy for the preparation of hollow polymeric nanosphere (HPN)-supported imidazolium-based ionic liquids (denoted as HPN-ILs) with superior antimicrobial activities. HPN-ILs were tailored by moderate Friedel-Crafts polymerization followed by the sequential covalent bonding of imidazole and bromoalkene. The resultant HPN-ILs have uniform hollow spherical morphology, an adequate surface area, and excellent physicochemical stability. Furthermore, they are highly active against both Gram-positive and Gram-negative bacteria and exhibit typical time/dosage-dependent antibacterial activities. The rational combination of porous HPNs and antibacterial ILs to generate an all-in-one entity may open new avenues for the design and fabrication of efficient bacteriostatic agents. Moreover, HPN-ILs have good biocompatibility and can also be loaded onto diverse matrices, and thus could extend their practical bactericidal application in the potential biomedical-active field. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 19980124
- Volume :
- 15
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- Nano Research
- Publication Type :
- Academic Journal
- Accession number :
- 157262502
- Full Text :
- https://doi.org/10.1007/s12274-022-4160-6