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Outcomes of successful vs. failed contemporary chronic total occlusion percutaneous coronary intervention.
- Source :
- Cardiovascular Intervention & Therapeutics; Jul2022, Vol. 37 Issue 3, p483-489, 7p
- Publication Year :
- 2022
-
Abstract
- Background: There are limited contemporary data on the impact of success vs. failure on the outcomes of chronic total occlusion (CTO) percutaneous coronary intervention (PCI). Methods: We conducted a systematic review and a meta-analysis of contemporary studies that compared the outcomes in patients who underwent successful vs. failed contemporary (2010 onwards) CTO PCI. We performed a sensitivity analysis limited to studies that started enrollment after the publication of the hybrid algorithm in 2012. Results: We included five studies with a total of 6,084 patients (successful CTO PCI n = 4,861, failed CTO PCI n = 1,223). During a median follow-up time of 12 months (range 6–60 months), successful CTO PCI was associated with a lower risk of major adverse cardiovascular events [OR: 0.61, 95% CI (0.41, 0.92), p = 0.02, I<superscript>2</superscript> = 63%] and all-cause death [OR: 0.57, 95% CI (0.33, 0.99), p = 0.05, I<superscript>2</superscript> = 60%]. Both groups had similar risk of myocardial infarction (MI) [OR 0.69, 95% CI (0.43, 1.10), p = 0.38, I<superscript>2</superscript> = 80%], target vessel revascularization (TVR) [OR: 0.56, 95% CI (0.25, 1.27), p = 0.17, I<superscript>2</superscript> = 80%], and stroke [OR: 0.52, 95% CI (0.14, 1.91), p = 0.33, I<superscript>2</superscript> = 0%]. Conclusion: In contemporary practice, successful CTO PCI was associated with a lower incidence of MACE driven by lower all-cause mortality compared with failed CTO PCI at a median follow-up of 1 year. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 18684300
- Volume :
- 37
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Cardiovascular Intervention & Therapeutics
- Publication Type :
- Academic Journal
- Accession number :
- 157431882
- Full Text :
- https://doi.org/10.1007/s12928-021-00819-x