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CIC::NUTM1 sarcoma mimicking primitive myxoid mesenchymal tumour of infancy: report of a case.

Authors :
Biederman, Laura E
Lee, Kristy
Yeager, Nicholas D
Sribnick, Eric A
Shenoy, Archana
Source :
Histopathology; Jul2022, Vol. 81 Issue 1, p131-133, 3p
Publication Year :
2022

Abstract

Next-generation sequencing with a custom Archer FusionPlex Pan-Solid Tumour assay, which utilizes anchored multiplex polymerase chain reaction (PCR) and unidirectional gene-specific primers (GSP2) to identify known or novel gene fusion partners, was performed (115 genes; Archer Part no. There have been several reports of I CIC i :: I NUTM1 i sarcomas,3-6 most of which occur in children.3 I NUTM1 i is the characteristic fusion gene seen in NUT-midline carcinomas, so a nosological dilemma may arise, especially as some of these tumours may express CKs. [Extracted from the article]

Details

Language :
English
ISSN :
03090167
Volume :
81
Issue :
1
Database :
Complementary Index
Journal :
Histopathology
Publication Type :
Academic Journal
Accession number :
157549528
Full Text :
https://doi.org/10.1111/his.14630