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Vagus nerve stimulation for super-refractory status epilepticus in febrile infection–related epilepsy syndrome: a pediatric case report and literature review.
- Source :
- Child's Nervous System; Jul2022, Vol. 38 Issue 7, p1401-1404, 4p
- Publication Year :
- 2022
-
Abstract
- Febrile infection–related epilepsy syndrome (FIRES) is a devastating epileptic encephalopathy with limited treatment options and unclear etiology. Vagus nerve stimulation (VNS) is an FDA-approved therapy for refractory epilepsy that has been shown to decrease the frequency and severity of seizures. There is a growing interest in alternate non-pharmaceutical therapies for managing super-refractory status epilepticus (SRSE). We present a 29-month-old case, diagnosed with FIRES, whose seizures were successfully controlled by utilization of VNS after ineffective response to intensive pharmacotherapy and ketogenic diet treatment. The VNS was planted after 14 days of refractory seizure activity with a following rapid parameter titration for 42 days without evident side effect, which finally controlled the seizure in the acute phase. VNS may be a potential candidate for the treatment of SRSE in FIRES. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 02567040
- Volume :
- 38
- Issue :
- 7
- Database :
- Complementary Index
- Journal :
- Child's Nervous System
- Publication Type :
- Academic Journal
- Accession number :
- 157687082
- Full Text :
- https://doi.org/10.1007/s00381-021-05410-6