Back to Search Start Over

Two new triterpenoids from the fruits of Aphanamixis polystachya.

Authors :
Wu, Shi-Li
Zou, Qiu-Ping
Xie, Xiao-Yan
Ren, Jia-Jia
Fan, Zhang
OuYang, Jing-Rong
Yin, Peng-Cheng
Dong, Fa-Wu
He, Hong-Ping
Source :
Journal of Asian Natural Products Research; Aug2022, Vol. 24 Issue 8, p738-745, 8p
Publication Year :
2022

Abstract

Two new triucallane triterpenoids, polystanin F (1) and polystanin G (2), along with eight known compounds (3-10) were isolated from the fruits of Aphanamixis polystachya. Their structures were established on the basis of extensive spectroscopic analysis. Moreover, eight compounds were evaluated for their in vitro cytotoxicity against three cancer cell lines (liver cancer RT112, colon cancer HCT-116 and breast cancer M231) using the MTT method. Compound 7 showed significant cytotoxic activity against HCT-116 with IC<subscript>50</subscript> 1.27 μM. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10286020
Volume :
24
Issue :
8
Database :
Complementary Index
Journal :
Journal of Asian Natural Products Research
Publication Type :
Academic Journal
Accession number :
158361129
Full Text :
https://doi.org/10.1080/10286020.2021.1972980