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T-cell responses to SARS-CoV-2 in healthy controls and primary immunodeficiency patients.
- Source :
- Clinical & Experimental Immunology; Mar2022, Vol. 207 Issue 3, p336-339, 4p
- Publication Year :
- 2022
-
Abstract
- Understanding the T-cell response to SARS-CoV-2 is key in patients who lack antibody production. We demonstrate the applicability of a functional assay to measure the T-cell response in a cohort of patients with immunodeficiency. T-cell responses to COVID are now linked to improved outcomes. This paper demonstrates a method to robustly test responses for routine diagnostic use in healthy controls and those unable to make a detectable antibody response due to underlying immune deficiency (primary or acquired). [ABSTRACT FROM AUTHOR]
- Subjects :
- T cells
SARS-CoV-2
ROUTINE diagnostic tests
IMMUNODEFICIENCY
ANTIBODY formation
Subjects
Details
- Language :
- English
- ISSN :
- 00099104
- Volume :
- 207
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Clinical & Experimental Immunology
- Publication Type :
- Academic Journal
- Accession number :
- 158572339
- Full Text :
- https://doi.org/10.1093/cei/uxac001