Back to Search
Start Over
Changing trends of splenectomy in hereditary spherocytosis: The experience of a reference Centre in the last 40 years.
- Source :
- British Journal of Haematology; Sep2022, Vol. 198 Issue 5, p912-915, 4p
- Publication Year :
- 2022
-
Abstract
- Summary: We describe the clinical/haematological characteristics of 446 patients with hereditary spherocytosis diagnosed in the last 40 years in a reference centre. The frequency of splenectomy decreased over time (44% before 1990 to 7% in 2011–2020), notwithstanding a confirmed good efficacy. Age at splenectomy progressively increased (63% in children before 1990 to 88% in patients aged ≥20 years in 2011–2020). Our real‐life experience showed that even a fraction of patients in the trait/mild categories (19/92, 21%) were splenectomised, whilst 30/78 (38%) in the moderate/severe groups were not. Overall, these data pinpoint to the increasing awareness about post‐splenectomy thromboses and infections. [ABSTRACT FROM AUTHOR]
- Subjects :
- SPLENECTOMY
AWARENESS
CHOLECYSTECTOMY
DIAGNOSIS
Subjects
Details
- Language :
- English
- ISSN :
- 00071048
- Volume :
- 198
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- British Journal of Haematology
- Publication Type :
- Academic Journal
- Accession number :
- 158655235
- Full Text :
- https://doi.org/10.1111/bjh.18106