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COVID-19 infection and renal injury: where is the place for acute interstitial nephritis disease?
- Source :
- Clinical Kidney Journal; Sep2022, Vol. 15 Issue 9, p1698-1704, 7p
- Publication Year :
- 2022
-
Abstract
- Novel coronavirus disease infection (coronavirus disease 2019, COVID-19) was declared a global pandemic in March 2020 and since then has become a major public health problem. The prevalence of COVID-19 infection and acute kidney injury (AKI) is variable depending on several factors such as race/ethnicity and severity of illness. The pathophysiology of renal involvement in COVID-19 infection is not entirely clear, but it could be in part explained by the viral tropism in the kidney parenchyma. AKI in COVID-19 infection can be either by direct invasion of the virus or as a consequence of immunologic response. Diverse studies have focused on the effect of COVID-19 on glomerulonephritis (GN) patients or the 'novo' GN; however, the effect of COVID-19 in acute tubulointerstitial nephritis (ATIN) has been scarcely studied. In this article, we present five cases with different spectrums of COVID-19 infection and ATIN that may suggest that recent diagnosis of ATIN is accompanied by a worse clinical prognosis in comparison with long-term diagnosed ATIN. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 20488505
- Volume :
- 15
- Issue :
- 9
- Database :
- Complementary Index
- Journal :
- Clinical Kidney Journal
- Publication Type :
- Academic Journal
- Accession number :
- 158805231
- Full Text :
- https://doi.org/10.1093/ckj/sfac079