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Infectious diseases associated with pediatric type 1 diabetes mellitus: A narrative review.

Authors :
Piccolo, Gianluca
De Rose, Elena Lucia
Bassi, Marta
Napoli, Flavia
Minuto, Nicola
Maghnie, Mohamad
Patti, Giuseppa
d'Annunzio, Giuseppe
Source :
Frontiers in Endocrinology; 8/24/2022, Vol. 13, p1-11, 11p
Publication Year :
2022

Abstract

Diabetes mellitus (DM) has been frequently associated with an impaired immune response against infectious agents, making affected patients at risk for more severe disease and sometimes causing worse outcomes. The recent COVID-19 pandemic has seriously affected patients with both diabetes, in particular those carrying comorbidities or with poor glycemic control. As regards pediatric diabetes mellitus, the availability of more accurate and technological tools for glycemic management and the improved markers of metabolic control might mitigate the negative impact of infections. Notably, good metabolic control of diabetes since its diagnosis reduces not only the risk of microangiopathic complications but also of impaired immune response to infectious diseases. Therefore, vaccinations are strongly recommended. Our paper aims to provide the most updated evidence regarding infectious diseases in type 1 pediatric DM. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
16642392
Volume :
13
Database :
Complementary Index
Journal :
Frontiers in Endocrinology
Publication Type :
Academic Journal
Accession number :
159073676
Full Text :
https://doi.org/10.3389/fendo.2022.966344