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Dual-strategy biosensing of glucose based on multifunctional CuWO4 nanoparticles.
- Source :
- Analyst; 9/21/2022, p4049-4054, 6p
- Publication Year :
- 2022
-
Abstract
- In this research, dual-strategy biosensing of glucose was proposed based on multifunctional CuWO<subscript>4</subscript> nanoparticles (CuWO<subscript>4</subscript> NPs), which were prepared for the application of electrochemical and colorimetric sensing of glucose. CuWO<subscript>4</subscript> NPs show large specific surface area and good conductivity as well as excellent peroxidase-like activity. A sensitive and selective electrochemical glucose biosensor was fabricated with the immobilization of glucose oxidase (GOx) on a CuWO<subscript>4</subscript> NP modified electrode for enhancing the direct electron transfer behavior. A wide linear range of 0.005–1.8 mM with a low detection limit of 1.5 μM and a high sensitivity of 28.02 mA M<superscript>−1</superscript> cm<superscript>−2</superscript> were achieved by using the electrochemical biosensor. Meanwhile, a colorimetric and visual glucose biosensor was constructed based on the GOx/CuWO<subscript>4</subscript> cascade nanozyme, which shows a linear range of 0.05–1.0 mM with excellent selectivity. CuWO<subscript>4</subscript> NPs as a promising matrix open up a dual-strategy biosensor for sensitive and selective detection of glucose. [ABSTRACT FROM AUTHOR]
- Subjects :
- GLUCOSE oxidase
GLUCOSE
CHARGE exchange
NANOPARTICLES
DETECTION limit
BIOSENSORS
Subjects
Details
- Language :
- English
- ISSN :
- 00032654
- Database :
- Complementary Index
- Journal :
- Analyst
- Publication Type :
- Academic Journal
- Accession number :
- 159084606
- Full Text :
- https://doi.org/10.1039/d2an01003h