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HLA Class-II-Specific T-Lymphocyte Clones with Dual Alloreactive Functions.
- Source :
- Scandinavian Journal of Immunology; Mar1984, Vol. 19 Issue 3, p237-245, 9p
- Publication Year :
- 1984
-
Abstract
- The relationship between T lymphocytes that proliferate in response to HLA class II antigens and those that mediate the cytotoxic response toward HLA class II target antigens was investigated. Alloreactive T-cell clones were derived under conditions in which the likelihood of clonality was high. Three populations of HLA class-II-specific T cells were identified. Two of these populations exhibited only HLA class-II-directed cytotoxicity or HLA class-II-induced proliferation. The third population of T cells exhibited both of these responses. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 03009475
- Volume :
- 19
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Scandinavian Journal of Immunology
- Publication Type :
- Academic Journal
- Accession number :
- 15908535
- Full Text :
- https://doi.org/10.1111/j.1365-3083.1984.tb00925.x