'Cold and Locked in': A frozen body and frozen eyes in end-stage ALS.

A case study of a 62‑year man presented with weakness of the right hand6 months earlier as electromyography had shown extensive denervation and reinnervation all the segments. Topics include Oculomotor abnormalities (OMA) are smooth pursuit and saccadic abnormalities followed by supranuclear ophthalmoplegia and total external ophthalmoplegia; and severe muscle loss precluded endothermic muscular heat generation necessary to maintain normothermia in a cold environment.