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Synthesis and crystal structure of topiramate azidosulfate at 90 K and 298 K.
- Source :
- Acta Crystallographica Section E: Crystallographic Communications; Oct2022, Vol. 78 Issue 10, p984-Sup-10, 15p
- Publication Year :
- 2022
-
Abstract
- The low (90 K) and room (298 K) temperature crystal structures of topiramate azidosulfate [systematic name 2,3:4,5-bis-O-(1-methylethylidene)-ß-D-fructopyranose azidosulfate], C12H19N<subscript>3</subscript>O8S, an intermediate in the synthesis of the anti-convulsant drug topiramate, are described. Topiramate azidosulfate (I) finds use as a reference impurity standard for topiramate. A modified synthesis and some spectroscopic details are also presented. [ABSTRACT FROM AUTHOR]
- Subjects :
- CRYSTAL structure
TOPIRAMATE
DRUG synthesis
Subjects
Details
- Language :
- English
- ISSN :
- 20569890
- Volume :
- 78
- Issue :
- 10
- Database :
- Complementary Index
- Journal :
- Acta Crystallographica Section E: Crystallographic Communications
- Publication Type :
- Academic Journal
- Accession number :
- 159543941
- Full Text :
- https://doi.org/10.1107/S2056989022008799