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Surgical Management of Melanoma: Advances and Updates.

Authors :
Santamaria-Barria, Juan A.
Mammen, Joshua M. V.
Source :
Current Oncology Reports; Nov2022, Vol. 24 Issue 11, p1425-1432, 8p
Publication Year :
2022

Abstract

Purpose of Review : To review and update surgeons about the evolving complexities in the surgical management of melanoma including lymph node staging and treatment. Recent Findings: Primary resection with adequate margins continues to be the standard of care for localized cutaneous melanoma. Sentinel lymph node biopsy is confirmed to be a powerful tool due to its prognostic value and informative guidance for adjuvant treatments and surveillance. Due to the lack of benefit in melanoma-specific survival and distant metastasis-free survival, completion lymph node dissection is not performed routinely after a positive sentinel lymph node biopsy. Neoadjuvant systemic treatment approaches for advanced loco-regional disease show promise in phase I and II clinical trial data, and phase III studies. Summary: The surgical management of cutaneous melanoma continues to evolve with further de-escalation of the extent of excision of primary melanomas and the management of lymph node disease. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
15233790
Volume :
24
Issue :
11
Database :
Complementary Index
Journal :
Current Oncology Reports
Publication Type :
Academic Journal
Accession number :
160707169
Full Text :
https://doi.org/10.1007/s11912-022-01289-x