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Association between Periodontitis and Aortic Calcification: A Cohort Study.
- Source :
- Angiology; Feb2023, Vol. 74 Issue 2, p129-138, 10p
- Publication Year :
- 2023
-
Abstract
- The present study investigated the association between the presence of periodontitis and aortic calcification (AC) risk among Chinese adults. A total of 6059 individuals who underwent regular health check-ups and received a diagnosis of periodontitis between 2009 and 2016 were included. The outcome was AC, assessed by a chest low-dose spiral CT scan. Cox proportional hazards regression analysis was used to assess the association between periodontitis and AC risk after adjusting for several confounders. After a median follow-up period of 2.3 years (interquartile range: 1.03–4.97 years), 843 cases of AC were identified, with 532 (12.13%) and 311 (18.59%) patients in the non-periodontitis group and periodontitis group, respectively. Multivariate analyses demonstrated that, compared with those without periodontitis, the hazard ratio and 95% confidence interval for AC risk in participants with periodontitis was 1.18 (1.02–1.36) (P =.025) in the fully adjusted model. Stratified analyses showed that the positive relationship between periodontitis and AC was more evident in males and participants <65 years of age (p<subscript>interaction</subscript> =.005 and.004, respectively). Our results show that the presence of periodontitis was positively associated with AC among Chinese adults, especially among males and younger participants. [ABSTRACT FROM AUTHOR]
- Subjects :
- CARDIOVASCULAR diseases risk factors
AORTIC diseases
CONFIDENCE intervals
PERIODONTITIS
MULTIVARIATE analysis
AGE distribution
REGRESSION analysis
RISK assessment
SEX distribution
CALCINOSIS
DESCRIPTIVE statistics
COMPUTED tomography
LONGITUDINAL method
PROPORTIONAL hazards models
DISEASE risk factors
DISEASE complications
ADULTS
Subjects
Details
- Language :
- English
- ISSN :
- 00033197
- Volume :
- 74
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Angiology
- Publication Type :
- Academic Journal
- Accession number :
- 160708616
- Full Text :
- https://doi.org/10.1177/00033197221094713