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Association between Periodontitis and Aortic Calcification: A Cohort Study.

Authors :
Yu, Ying-lin
Ma, Jun-rong
Li, Shu-na
Liao, Min-qi
Xu, Shan
Chen, Hong-en
Dai, Shu-hong
Peng, Xiao-lin
Zhao, Dan
Lou, Yan-mei
Yu, Xiao-xuan
Gao, Xu-ping
Liu, Yan-hua
Liu, Jun
Ke, Xing-yao
Ping, Zhao
Wang, Li
Wang, Chang-yi
Zeng, Fang-fang
Source :
Angiology; Feb2023, Vol. 74 Issue 2, p129-138, 10p
Publication Year :
2023

Abstract

The present study investigated the association between the presence of periodontitis and aortic calcification (AC) risk among Chinese adults. A total of 6059 individuals who underwent regular health check-ups and received a diagnosis of periodontitis between 2009 and 2016 were included. The outcome was AC, assessed by a chest low-dose spiral CT scan. Cox proportional hazards regression analysis was used to assess the association between periodontitis and AC risk after adjusting for several confounders. After a median follow-up period of 2.3 years (interquartile range: 1.03–4.97 years), 843 cases of AC were identified, with 532 (12.13%) and 311 (18.59%) patients in the non-periodontitis group and periodontitis group, respectively. Multivariate analyses demonstrated that, compared with those without periodontitis, the hazard ratio and 95% confidence interval for AC risk in participants with periodontitis was 1.18 (1.02–1.36) (P =.025) in the fully adjusted model. Stratified analyses showed that the positive relationship between periodontitis and AC was more evident in males and participants <65 years of age (p<subscript>interaction</subscript> =.005 and.004, respectively). Our results show that the presence of periodontitis was positively associated with AC among Chinese adults, especially among males and younger participants. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00033197
Volume :
74
Issue :
2
Database :
Complementary Index
Journal :
Angiology
Publication Type :
Academic Journal
Accession number :
160708616
Full Text :
https://doi.org/10.1177/00033197221094713