Production standardization of hand sanitizer spray based on ethanol, isopropanol, and bioethanol to prevent the COVID-19 transmission.

This study was conducted to evaluate the performance of an alcohol-based hand sanitizer spray as an affordable antimicrobial agent for controlling the spread of COVID-19. In this research, hand sanitizer spray was made from 70% alcohol as active ingredient; glycerol 11.65%; IPM 0.77%; essential oil 0.19%; and distilled water 17.39%. To determine the quality of hand sanitizer spray, organoleptic, homogeneity, pH, density, viscosity, dispersibility, adhesion, dry time, and anti-bacterial activity tests were carried out. The results of the organoleptic analysis showed that the preparation was liquid, clear in color with a distinctive aroma of coffee, and a pH of 6.5 - 7.0. Homogeneity of the preparations showed the stability of the constituent components of the emulsion with a density of 0.8-0.83 g/cm3, a viscosity of 2.5-4.0 cP, with a spreadability of 13-17 cm and adhesion of more than 1 second. Hand sanitizer spray products also show antibacterial activity against Eschericia coli, Staphylococcus aureus and Salmonella thypimurium. [ABSTRACT FROM AUTHOR]