Global Research Trend in Vaccine Design.

The current study established a research mapping of the vaccine design using bibliometric indicators and network visualization. For an analysis of the result, the study retrieved a total of 5379 documents from Scopus from 1983 to 2021. The study used the VOS Viewer and the RStudio tools for data visualization. The findings revealed that there has been significant growth in literature on vaccine design in the last two decades; in the last ten years, the year with the most publications were 2020, with 477 publications, and the highest had a total of 14,145 citations. D.R. Burton was ranked as the most prolific author, with 86 publications and 18,449 total citations and was observed as the most frequently published author in the domain. The National Institute of Health (NIH) was the most productive organization in the domain, with 266 publications. The document entitled "Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae" received a total of 1398 citations, and was the most cited document in the field of vaccine design. In network visualization, an analysis of the co-occurrence of keywords showed that "vaccine" and "vaccine design" occurred the most, which was 761 and 335 times, respectively. The study also observed that there were five clusters of author collaboration with a maximum of 18 authors and a minimum of two authors. The findings of the study will aid scholarly coalitions in the domains of medicine and health, information science and bibliometric professionals to carry out further research in the area of vaccine design. [ABSTRACT FROM AUTHOR]