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Outbreak of acute respiratory disease caused by human adenovirus type 7 and human coronavirus‐229E in Zhejiang Province, China.
- Source :
- Journal of Medical Virology; Jan2023, Vol. 95 Issue 1, p1-12, 12p
- Publication Year :
- 2023
-
Abstract
- In 2019, an outbreak of pharyngoconjunctival fever (PCF) occurred at a swimming center in Zhejiang Province, China. A total of 97 (13.55%) of the 716 amateur swimmers had illnesses, with 24 patients (24.74%) hospitalized in the pediatric ward. Human adenovirus serotype 7 (HAdV‐7) was isolated from one concentrated water from the swimming pool, and 20 of 97 positive cases without liver damage. This outbreak led to a nosocomial outbreak in the pediatric ward, in which 1 nurse had a fever and was confirmed to be adenovirus positive. The hexon, fiber, and penton genes from 20 outbreak cases, 1 water sample, and 1 nurse had 100% homology. Furthermore, 2 cases admitted to the pediatric ward, 2 parents, and 1 doctor were confirmed to be human coronaviruses (HCoV‐229E) positive. Finally, all outbreak cases had fully recovered, regardless of a single infection (adenovirus or HCoV‐229E) or coinfection of these two viruses simultaneously. Thus, PCF and acute respiratory disease outbreaks in Zhejiang were caused by the completely homologous type 7 adenovirus and HCoV‐229E, respectively. The swimming pool water contaminated with HAdV‐7 was most likely the source of the PCF outbreak, whereas nosocomial transmission might be the source of HCoV‐229E outbreak. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01466615
- Volume :
- 95
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Journal of Medical Virology
- Publication Type :
- Academic Journal
- Accession number :
- 161181429
- Full Text :
- https://doi.org/10.1002/jmv.28101