Back to Search
Start Over
Colony Formation by Subpopulations of Human T Lymphocytes II. Characteristics of Colony Cells and Colony Suppressor Cells.
- Source :
- Scandinavian Journal of Immunology; Apr1981, Vol. 13 Issue 4, p395-400, 6p
- Publication Year :
- 1981
-
Abstract
- Phytohaemagglutinin-induced human T-lymphocyte colony formation in semisolid agar culture is the property of erythrocyte rosette-forming cells (E-RFC) negative for the 7S IgG receptor (FcR-), E-RFC positive for the 7S IgG receptor (FcR-), on the other hand, exhibit a limited capacity for colony formation and suppress colonies formed by FcR- E-RFC. T colonies are composed of small lymphocytes and lymphoblasts, the vast majority being negative for the Fc receptor. Most colony cells (86%) carry the Leu 3a antigen, suggesting that they belong to the inducer/helper T-cell subset. FcR<superscript>+</superscript> colony suppressor cells are small, slowly sedimenting cells (sedimentation velocity <3.8 mm/h) and are strongly adherent to plastic, and their activity depends on the ability to synthesize DNA. [ABSTRACT FROM AUTHOR]
- Subjects :
- PHYTOHEMAGGLUTININS
AGAR
T cells
CELLS
ANTIGENS
LYMPHOCYTES
Subjects
Details
- Language :
- English
- ISSN :
- 03009475
- Volume :
- 13
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Scandinavian Journal of Immunology
- Publication Type :
- Academic Journal
- Accession number :
- 16169294
- Full Text :
- https://doi.org/10.1111/j.1365-3083.1981.tb00150.x