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Molecular Aspects of Allergen-Specific Immunotherapy in Patients with Seasonal Allergic Rhinitis.
- Source :
- Cells (2073-4409); Feb2023, Vol. 12 Issue 3, p383, 17p
- Publication Year :
- 2023
-
Abstract
- A systematic review and narrative synthesis of publications was undertaken to analyze the role of component-resolved diagnosis technology in identifying polysensitization for the provision of allergen-specific immunotherapy to patients with seasonal allergic rhinitis. A search of publications was carried out in electronic databases in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The search helped to identify 568 publications, 12 of which were included in this review. Overall, 3302 patients were enrolled. The major finding was that component-resolved diagnostics change the choice of relevant allergens for allergen-specific immunotherapy in at least 50% of cases. Sensitization to allergen components differs with age, type of disease, and overall disease duration. Patients who had both bronchial asthma and allergic rhinitis were sensitized to a larger number of allergens than patients who had bronchial asthma alone. [ABSTRACT FROM AUTHOR]
- Subjects :
- ALLERGENS
ALLERGIC rhinitis
ASTHMA
SEASONS
IMMUNOTHERAPY
DISEASE duration
Subjects
Details
- Language :
- English
- ISSN :
- 20734409
- Volume :
- 12
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Cells (2073-4409)
- Publication Type :
- Academic Journal
- Accession number :
- 161818564
- Full Text :
- https://doi.org/10.3390/cells12030383