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Metabolite Profiling and Bioactivities of Leaves, Stems, and Flowers of Rumex usambarensis (Dammer) Dammer, a Traditional African Medicinal Plant.

Authors :
Spaggiari, Chiara
Righetti, Laura
Spadini, Costanza
Annunziato, Giannamaria
Nsanzurwimo, Aimable
Cabassi, Clotilde Silvia
Bruni, Renato
Costantino, Gabriele
Source :
Plants (2223-7747); Feb2023, Vol. 12 Issue 3, p482, 15p
Publication Year :
2023

Abstract

The comprehensive identification of secondary metabolites represents a fundamental step for the assessment of bioactivities and pharmacological properties of traditional herbal drugs. Rumex usambarensis (Dammer) Dammer has been described as a multipurpose remedy in different African traditional pharmacopoeias, but its phytochemical profile has not been properly investigated. Herein we report a high throughput metabolomic screening, based on ultra-high performance liquid chromatography-travelling wave ion mobility spectrometry quadrupole time-of-flight (UHPLC-TWINS-QTOF), which was performed for the first time on different R. usambarensis plant parts. By applying high-resolution mass spectrometry-based metabolomics and chemometric analysis, a complete discrimination of different aerial parts was obtained, with the annotation of 153 significant metabolites in leaves, stems, and flowers, suggesting an easy authentication and discrimination route. Phytochemical data were correlated to antimicrobial and antioxidant properties. Flavonoids, benzopyranes, chromones, and xanthones derivatives, along with a richer phytocomplex, might be responsible for the stronger bioactivities obtained from flowers. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
22237747
Volume :
12
Issue :
3
Database :
Complementary Index
Journal :
Plants (2223-7747)
Publication Type :
Academic Journal
Accession number :
161872234
Full Text :
https://doi.org/10.3390/plants12030482