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Use of drug-coated balloon instead of drug-eluting stent for pediatric cardiac allograft vasculopathy.
- Source :
- Annals of Pediatric Cardiology; Jan/Feb2023, Vol. 16 Issue 1, p45-47, 3p
- Publication Year :
- 2023
-
Abstract
- Cardiac allograft vasculopathy (CAV) sometimes leads to restenosis, even after percutaneous transcatheter intervention. Recently, drug-coated balloons (DCBs) have been successfully used to treat coronary artery disease, especially CAVs, in adults. However, no studies have used DCBs in pediatric CAVs. We encountered a patient with CAV who underwent cardiac transplantation for restrictive cardiomyopathy at the age of 2 years. Nine years after the transplantation, severe stenosis of the proximal left anterior descending branch was observed. Considering the patient's young age and the possibility of restenosis, we performed an intervention with DCB. Follow-up conducted 7 months after the intervention showed no restenosis. Cardiac coronary artery lesions following transplantation are more likely to result in restenosis earlier than arteriosclerotic lesions. In pediatric patients, restenosis might require multiple stents and prolonged antiplatelet therapy. Our findings provide evidence supporting the possibility of an effective treatment of CAV in children. [ABSTRACT FROM AUTHOR]
- Subjects :
- CARDIOVASCULAR surgery
DRUG delivery systems
PATIENT aftercare
HOMOGRAFTS
TRANSLUMINAL angioplasty
DRUG-eluting stents
CARDIOMYOPATHIES
SURGICAL stents
CORONARY restenosis
PEDIATRIC cardiology
TREATMENT effectiveness
EVEROLIMUS
CORONARY artery disease
IMMUNOSUPPRESSIVE agents
VASCULAR diseases
HEART diseases
TACROLIMUS
EQUIPMENT & supplies
Subjects
Details
- Language :
- English
- ISSN :
- 09742069
- Volume :
- 16
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Annals of Pediatric Cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 162999529
- Full Text :
- https://doi.org/10.4103/apc.apc_47_22