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Molecular characterization of porcine circovirus 2 circulating in Assam and Arunachal Pradesh of India.

Authors :
D'silva, Ajai Lawrence
Bharali, Arpita
Buragohain, Lukumoni
Pathak, Dinesh C.
Ramamurthy, Narayan
Batheja, Rahul
Mariappan, Asok Kumar
Gogoi, Sophia M.
Barman, Nagendra Nath
Dey, Sohini
Chellappa, Madhan Mohan
Source :
Animal Biotechnology; Apr2023, Vol. 34 Issue 2, p462-466, 5p
Publication Year :
2023

Abstract

PCV2 is the primary etiological agent of porcine circovirus-associated diseases (PCVADs) which affect pigs worldwide. Currently, there is a worldwide genotype prevalence switch from PCV2b to PCV2d, which has led to increased virulence of the circulating virus strains leading to vaccine failures and selection pressure. In the present study, the PCV2 genotypes circulating in north eastern region (NER) of India particularly the states of Assam and Arunachal Pradesh was characterized by isolation, sequencing and phylogenetic analysis of cap gene. The phylogenetic analysis revealed that the PCV2 isolates circulating in pigs of Assam and Arunachal Pradesh were mostly of PCV2d genotype. Hence, it can be concluded that PCV2d genotype is the most dominating genotype in NER and priority should be given to this genotype for development of future vaccine candidate against PCV2 in India. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10495398
Volume :
34
Issue :
2
Database :
Complementary Index
Journal :
Animal Biotechnology
Publication Type :
Academic Journal
Accession number :
163091354
Full Text :
https://doi.org/10.1080/10495398.2021.1955700