Innenrücktitelbild: Endogenous Enzyme‐Operated Spherical Nucleic Acids for Cell‐Selective Protein Capture and Localization Regulation (Angew. Chem. 18/2023).

Cancer Cell Specificity, Enzymes, Protein Function Regulation, Spherical Nucleic Acids, Subcellular Translocation The system enables enzyme-activated capture of proteins of interest and thus regulation of their cytoplasmic-nuclear shuttling with tumor-cell specificity, as reported by Mengyuan Li and co-workers in their Research Article (e202214958). Keywords: Cancer Cell Specificity; Enzymes; Protein Function Regulation; Spherical Nucleic Acids; Subcellular Translocation EN Cancer Cell Specificity Enzymes Protein Function Regulation Spherical Nucleic Acids Subcellular Translocation 1 1 1 04/18/23 20230424 NES 230424 B Cell-selective regulation b of protein translocation is achieved through the rational design of an endogenous enzyme-operated spherical nucleic acids platform. [Extracted from the article]