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Association between visceral adiposity index and heart failure: A cross-sectional study.
- Source :
- Clinical Cardiology; Mar2023, Vol. 46 Issue 3, p310-319, 10p
- Publication Year :
- 2023
-
Abstract
- Background: Obesity is an important risk factor for heart failure (HF). Hypothesis: Visceral adiposity index (VAI) is a simple metric for assessing obesity; however, the association between VAI and risk for HF has not been studied. Methods: A cross-sectional study involving 28 764 participants =18 years of age from the National Health and Nutrition Examination Survey (NHANES), 2009-2018, in the United States was performed. VAI was calculated using body mass index (BMI), waist circumference (WC), triglycerides (TG), and high-density lipoprotein cholesterol. VAI was analyzed as a continuous and categorical variable to examine its association with HF. Subgroup analysis was also performed. Results: The highest VAI (fourth quartile [Q4]) was found among males, BMI, systolic and diastolic blood pressure, WC, hypertension, diabetes, liver disease, coronary heart disease, smoking, total cholesterol, and TG. More participants in Q4 took ß-receptor blockers, angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers/angiotensin receptor-neprilysin inhibitor, calcium channel blockers, and antidiabetic and antihyperlipidemic medications. Participants with HF exhibited greater VAI. A per-unit increase in VAI resulted in a 4% increased risk for HF (odds ratio [OR] 1.04 [95% confidence interval (CI) 1.02-1.05]). After multivariable adjustment, compared with the lowest quartile, the OR for Q3 was 1.55 (95% CI 1.24-1.94). Subgroup analysis revealed no significant interactions between VAI and specific subgroups. Conclusion: VAI was independently associated with the risk for HF. As a noninvasive index of visceral adiposity, VAI could be used for a "one shot" assessment of HF risk and may serve as a novel marker. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01609289
- Volume :
- 46
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Clinical Cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 163133655
- Full Text :
- https://doi.org/10.1002/clc.23976