Back to Search
Start Over
Assessing nocturnal scratch with actigraphy in atopic dermatitis patients.
- Source :
- NPJ Digital Medicine; 4/26/2023, Vol. 6 Issue 1, p1-12, 12p
- Publication Year :
- 2023
-
Abstract
- Nocturnal scratch is one major factor leading to impaired quality of life in atopic dermatitis (AD) patients. Therefore, objectively quantifying nocturnal scratch events aids in assessing the disease state, treatment effect, and AD patients' quality of life. In this paper, we describe the use of actigraphy, highly predictive topological features, and a model-ensembling approach to develop an assessment of nocturnal scratch events by measuring scratch duration and intensity. Our assessment is tested in a clinical setting against the ground truth obtained from video recordings. The new approach addresses unmet challenges in existing studies, such as the lack of generalizability to real-world applications, the failure to capture finger scratches, and the limitations in the evaluation due to imbalanced data in the current literature. Furthermore, the performance evaluation shows agreement between derived digital endpoints and the video annotation ground truth, as well as patient-reported outcomes, which demonstrated the validity of the new assessment of nocturnal scratch. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 23986352
- Volume :
- 6
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- NPJ Digital Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 163335217
- Full Text :
- https://doi.org/10.1038/s41746-023-00821-y