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Naftidrofuryl in Chronic Arterial Disease. Results of a Controlled Multicenter Study.

Authors :
Trubestein, G.
.Bohme, H
Heidrich, H.
Heinrich, F.
Hirche, H.
Maass, U.
Mori, H.
Rudofsky, G.
Source :
Angiology; Nov1984, Vol. 35 Issue 11, p701-708, 8p
Publication Year :
1984

Abstract

In a double blind, randomized multicenter study naftidrofuryl, a vasoactive substance, was compared with placebo in the treatment of 104 patients with chronic arterial occlusive disease. After a run-in period of four weeks the patients received either naftidrofuryl (600mg daily) or placebo over 12 weeks. The pain-free and the total walking distances improved significantly in both groups. However, the difference in the improvement of the pain-free walking distance was significant (p < 0.02) in favour of naftidrofuryl. There also was a difference in the improvement of the total walking distance in favour of naftidrofuryl which was not significant. The results indicate that naftidrofuryl has a beneficial effect on the symp- toms and lengthens the painfree walking distance in patients with arterial occlusive disease. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00033197
Volume :
35
Issue :
11
Database :
Complementary Index
Journal :
Angiology
Publication Type :
Academic Journal
Accession number :
16352893