University of Tubingen Reports Findings in Generalized Epilepsy.

Keywords: Tuebingen; Germany; Europe; Brain Diseases and Conditions; Central Nervous System Diseases and Conditions; Drugs and Therapies; Epilepsy; Epileptic Encephalopathy; Generalized Epilepsy; Genetics; Health and Medicine; Nervous System Diseases and Conditions; Neurologic Manifestations; Seizures; Therapeutics; Therapy EN Tuebingen Germany Europe Brain Diseases and Conditions Central Nervous System Diseases and Conditions Drugs and Therapies Epilepsy Epileptic Encephalopathy Generalized Epilepsy Genetics Health and Medicine Nervous System Diseases and Conditions Neurologic Manifestations Seizures Therapeutics Therapy N.PAG N.PAG 1 05/08/23 20230508 NES 230508 2023 MAY 9 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Vaccine Week -- New research on Central Nervous System Diseases and Conditions - Generalized Epilepsy is the subject of a report. Two variants causing developmental and epileptic encephalopathy showed a strong gain-of-function (hyperpolarizing shift of steady-state activation, strongly increased neuronal firing rate) and one variant causing benign familial infantile epilepsy or intermediate epilepsy showed a mild gain-of-function (defective fast inactivation, less increased firing). [Extracted from the article]