Approaches to vascularizing human brain organoids.

A major challenge in brain organoid technologies is the lack of vasculature. In recent years, innovative approaches have been taken to meet this challenge. A 2020 paper published in PLOS Biology exemplifies the approaches used in this booming field. The development of brain organoids has been a boon to neurological research, but working out how to add blood vessels to organoids has posed a challenge. This Perspective looks at innovative approaches to brain organoid vascularization, including those put forward in a 2020 PLOS Biology paper. [ABSTRACT FROM AUTHOR]