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Complete 1H and 13C assignments of two new sesquiterpenoids from Dendrobium aduncum.

Authors :
Huang, Lang
Meng, Yu‐Fan
Wang, Gang
Yang, Jian‐wen
Zhang, Mao‐Sheng
Dong, Min‐Jian
Sun, Cheng‐Xin
Xiao, Shi‐Ji
Source :
Magnetic Resonance in Chemistry; Jun2023, Vol. 61 Issue 6, p386-391, 6p
Publication Year :
2023

Abstract

Two new sesquiterpenoids, dendroaduoid A (1) and dendroaduol (2), together with four known sesquiterpenoids were isolated from the stems of Dendrobium aduncum. Their structures were identified by HR‐ESI‐MS and NMR experiments, and the complete assignments of 1H and 13C NMR data for two new sesquiterpenoids were obtained by the aid of HSQC, HMBC, 1H‐1H COSY, NOESY, and ECD techniques. The cytotoxic effects of the isolated compounds on four tumor cell lines (HCT‐116, HepG2, A549, and SW1990) were evaluated using MTT assay. Otherwise, the inhibitory activity of these six sesquiterpenoids on glycosidase was also evaluated. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
07491581
Volume :
61
Issue :
6
Database :
Complementary Index
Journal :
Magnetic Resonance in Chemistry
Publication Type :
Academic Journal
Accession number :
163632363
Full Text :
https://doi.org/10.1002/mrc.5345