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Efficacy of frankincense‐based herbal product in urinary incontinence: A randomized, double‐blind, placebo‐ and active‐controlled clinical trial.

Authors :
Karbalaiee, Mahbubeh
Daneshpajooh, Azar
Khanjani, Narges
Sohbati, Samira
Mehrabani, Mehrnaz
Mehrbani, Mehrzad
Mehrabani, Mitra
Source :
Phytotherapy Research; May2023, Vol. 37 Issue 5, p1754-1770, 17p
Publication Year :
2023

Abstract

Urinary incontinence is a silent epidemic that has a serious impact on a person's quality of life (QOL). This study aimed to evaluate the efficacy of frankincense‐based herbal product (FHP) in urinary incontinence compared with placebo and solifenacin. In this randomized, double‐blind clinical trial, 120 postmenopausal women with mixed urinary incontinence were randomized to one of the three groups of FHP, placebo, and standard treatment (solifenacin). Frequency, amount of leakage, and score of urinary incontinence as well as the QOL were measured at the end of the second and fourth weeks and 2 weeks after the interruption of the treatment. The ICIQ‐UI SF and I‐QOL questionnaires were used for the measurements. Mean frequency of urinary incontinence and amount of leakage significantly decreased in the FHP and solifenacin groups in the fourth week compared to the placebo group. In addition, 2 weeks after treatment completion, the effects of the FHP were significant compared to the solifenacin group. Due to the effect of FHP on improving the QOL and also the prolonged effect of this drug, the use of FHP in urinary incontinence, as a complementary treatment could be suggested. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0951418X
Volume :
37
Issue :
5
Database :
Complementary Index
Journal :
Phytotherapy Research
Publication Type :
Academic Journal
Accession number :
163632366
Full Text :
https://doi.org/10.1002/ptr.7691