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Fabrication and characterization of porous tissue‐mimicking optical phantoms as a tool for optical sensor validation.

Authors :
Joseph, Manju
Van Hileghem, Lorenz
Postelmans, Annelies
Lammertyn, Jeroen
Saeys, Wouter
Source :
Journal of Biophotonics; Jun2023, Vol. 16 Issue 6, p1-11, 11p
Publication Year :
2023

Abstract

This paper presents porous polydimethylsiloxane (PDMS) optical phantoms with tunable microstructural and optical properties to mimic porous biological tissues (e.g., fruit) during the design and optimization of novel optical setups. A well connected salt network formed using salt particles of various size distributions was used to obtain porous PDMS phantoms of different porous features including porosity, pore size distribution, pore number density and pore connectivity. These microstructural features are strongly related to the light scattering from the phantom where a higher reduced scattering coefficient (μs′) was observed from the porous PDMS phantom with a higher number of small pores compared to the optical phantom with a lower number of larger pores. The prepared phantoms were used to validate GASMAS (gas in scattering media absorption spectroscopy) H2O and O2 sensors by quantifying the optical path length through the pores and the O2 concentration inside the pores. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
1864063X
Volume :
16
Issue :
6
Database :
Complementary Index
Journal :
Journal of Biophotonics
Publication Type :
Academic Journal
Accession number :
164115869
Full Text :
https://doi.org/10.1002/jbio.202200338