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CC‐99282 plus R‐CHOP in patients (pts) with previously untreated aggressive B‐cell lymphoma (a‐BCL): early safety and efficacy results from a phase 1b study.

Authors :
Munoz, J.
Hoffmann, M.
Westin, J.
Vassilakopoulos, T. P.
García‐Sancho, A. M.
Rueda‐Domínguez, A.
Jurczak, W.
Kwiatek, M.
Bouzani, M.
Gkasiamis, A.
Patel, A.
Boucaud, F.
Li, J.
Nowakowski, G. S.
Source :
Hematological Oncology; Jun2023 Supplement 1, Vol. 41, p584-586, 3p
Publication Year :
2023

Abstract

CC-99282 plus R-CHOP in patients (pts) with previously untreated aggressive B-cell lymphoma (a-BCL): early safety and efficacy results from a phase 1b study CC-220-DLBCL-001 (NCT04884035) is an open-label, multicenter, dose-escalation and expansion trial to assess safety and preliminary efficacy of CC-99282 or CC-220 plus R-CHOP for untreated a-BCL. B Introduction: b Up to 30-40% of pts with diffuse large BCL relapse/become refractory after first-line chemo-immunotherapy with R-CHOP. [Extracted from the article]

Details

Language :
English
ISSN :
02780232
Volume :
41
Database :
Complementary Index
Journal :
Hematological Oncology
Publication Type :
Academic Journal
Accession number :
164231262
Full Text :
https://doi.org/10.1002/hon.3164_438