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MAHOGANY: A PHASE 3 TRIAL OF ZANUBRUTINIB PLUS ANTI‐CD20 VERSUS LENALIDOMIDE PLUS RITUXIMAB IN PATIENTS WITH RELAPSED/REFRACTORY FOLLICULAR OR MARGINAL ZONE LYMPHOMA.

Authors :
Sehn, L.
Sarkozy, C.
Song, Y.
Salar, A.
Trotman, J.
Zinzani, P. L.
Zhang, J.
Zhang, W.
Fustier, P.
Delarue, R.
Nastoupil, L.
Source :
Hematological Oncology; Jun2023 Supplement 1, Vol. 41, p168-170, 3p
Publication Year :
2023

Abstract

Zanubrutinib is approved in >15 countries, including the United States and European Union, for pts with relapsed/refractory ( I R i / I R i ) marginal zone lymphoma (MZL) who received >=1 anti-CD20-based regimen, based on the single-arm MAGNOLIA trial (Opat et al. I Clin Cancer Res i 2021). B Introduction: b Inhibition of Bruton tyrosine kinase (BTK) has emerged as a strategy for treatment of patients (pts) with B-cell malignancies including indolent non-Hodgkin lymphomas. MAHOGANY: A PHASE 3 TRIAL OF ZANUBRUTINIB PLUS ANTI-CD20 VERSUS LENALIDOMIDE PLUS RITUXIMAB IN PATIENTS WITH RELAPSED/REFRACTORY FOLLICULAR OR MARGINAL ZONE LYMPHOMA. [Extracted from the article]

Details

Language :
English
ISSN :
02780232
Volume :
41
Database :
Complementary Index
Journal :
Hematological Oncology
Publication Type :
Academic Journal
Accession number :
164231569
Full Text :
https://doi.org/10.1002/hon.3163_T04