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Diagnostic accuracy of whole heart coronary magnetic resonance angiography: a systematic review and meta-analysis.
- Source :
- Journal of Cardiovascular Magnetic Resonance (BioMed Central); 6/26/2023, Vol. 25 Issue 1, p1-13, 13p
- Publication Year :
- 2023
-
Abstract
- Background: The purpose of this meta-analysis was to comprehensively investigate the diagnostic ability of 1.5 T and 3.0 T whole heart coronary angiography (WHCA) to detect significant coronary artery disease (CAD) on X-ray coronary angiography. Methods: A literature search of electronic databases, including PubMed, Web of Science Core Collection, Cochrane advanced search, and EMBASE, was performed to retrieve and integrate articles showing significant CAD detectability of 1.5 and 3.0 T WHCA. Results: Data from 1899 patients from 34 studies were included in the meta-analysis. 1.5 T WHCA had a summary area under ROC of 0.88 in the patient-based analysis, 0.90 in the vessel-based analysis, and 0.92 in the segment-based analysis. These values for 3.0 T WHCA were 0.94, 0.95, 0.96, respectively. Contrast-enhanced 3.0 T WHCA had significantly higher specificity than non-contrast-enhanced 1.5 T WHCA on a patient-based analysis (0.87, 95% CI 0.80–0.92 vs. 0.74, 95% CI 0.64–0.82, P = 0.02). There were no differences in diagnostic performance on a patient-based analysis by use of vasodilators, beta-blockers or between Asian and Western countries. Conclusions: The diagnostic performance of WHCA was deemed satisfactory, with contrast-enhanced 3.0 T WHCA exhibiting higher specificity compared to non-contrast-enhanced 1.5 T WHCA in a patient-based analysis. There were no significant differences in diagnostic performance on a patient-based analysis in terms of vasodilator or beta-blocker use, nor between Asian and Western countries. However, further large-scale multicentre studies are crucial for the widespread global adoption of WHCA. [ABSTRACT FROM AUTHOR]
- Subjects :
- MAGNETIC resonance angiography
EVALUATION of medical care
ONLINE information services
MEDICAL databases
META-analysis
MEDICAL information storage & retrieval systems
CONFIDENCE intervals
SYSTEMATIC reviews
CONTRAST media
CORONARY angiography
CORONARY artery disease
RESEARCH funding
DESCRIPTIVE statistics
SENSITIVITY & specificity (Statistics)
MEDLINE
MAGNETIC fields
RECEIVER operating characteristic curves
EVALUATION
Subjects
Details
- Language :
- English
- ISSN :
- 1532429X
- Volume :
- 25
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Journal of Cardiovascular Magnetic Resonance (BioMed Central)
- Publication Type :
- Academic Journal
- Accession number :
- 164488318
- Full Text :
- https://doi.org/10.1186/s12968-023-00949-6